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Implanting for a better life

Wednesday 26 May 2004 09:32

Healthy Aims is a European programme with €16m from the European Commission's Sixth Framework fund which is looking at using technology, particularly implanted devices, to improve health.

"It aims to develop a range of implants and measurement methods to improve the health of people, mostly the disabled," says Dr. Diana Hodgins of European Technology for Business (ETB), who heads the programme.

The idea for Healthy Aims came out of an earlier part-EC-funded project: NEXUS (Network of Excellence in µ-systems).

NEXUS includes user-supplier collaborative clubs, including automotive, pharmaceutical and telecom clubs, set-up to connect technology suppliers and end-users, says Hodgins, who pulled together a 'medical devices' user club to add to the list two and a half years ago.

"The club was running for six months when I heard the call under the Information Society Technology section of Framework Six to look at microsystems," she says. "I went to the user supply club and asked if anybody was interested in a new project."

Enthusiasm for medical implants was strong and, nine months later, a proposal was submitted for Sixth Framework funding. "We were told we had the funding in July last year and Healthy Aims was started on December 1st."

Although it is early in the programme's four-year term, some significant work is already under way.

"IIP-Technologies in Germany is answering fundamental questions in the early research phase of a retinal implant project," says Hodgins. IIP has impressed external investors enough to attract €4.5m of venture funding to add to its €1.6m from Healthy Aims.

Cochlear implants are another device under investigation. "Two out of three Cochlear implant companies in the world are in Europe," says Hodgins, "and we have one of the two in Healthy Aims - Cochlear Technology Centre from Belgium."

A next-generation cochlear implant is one of the projects expected to produce something close to a product by the end of the programme. "The improved cochlear implant should be ready to go to market," says Hodgins.

Products are the aim of the programme. "At the end we expect to see some projects in this state and some in early pilot trials. We are trying to avoid developments that don't lead to a product."

This said, collaboration is the name of the game and some programme members will only be developing an element of another organisation's product. Bio-compatible materials are one case. "There are very few bio-materials available and anything we develop could be offered for future products," says Hodgins.

Queen Mary and Westfield College at the University of London, and the University of Newcastle-upon-Tyne could both have portfolios of new bio-compatible material in four years time as a result of co-operative development and testing with other programme members.
Bio-fuel-cells could also get a boost, with IMTEK (Institute of Microsystem Technology) in Germany and Spain's Universitat Rovira I Virgili looking at ways to power implants over the long term.

Existing bio-fuel-cells, all experimental, produce only minute amounts of power. "We need an order of magnitude improvement," says Hodgins, "but at least we know how much to aim for because it is others in the programme that use it."

In the nearer term, battery company Saft has joined, looking to improve more conventional re-chargeable cell technology for in-body use.

As well as managing Healthy Aims, Hodgins' ETB is working on its own implant technology. "We are developing a sphincter sensor, for the oesophagus first, but all sphincters are similar," she says. "I can't say how we are doing it, but ours is not using a conventional pressure sensor system."

There is also a movement sensor for limb control combining an accelerometer from ETB and gyros from other programme members.
To go with the sphincter sensor, ETB is developing an automatic valve to replace the urethral sphincter. "It will be a true intra-urethral sphincter," says Hodgins. "It has to be automatic because some people do not have the intellectual capability to operate this kind of thing manually."

The idea is to process yet-to-be-defined external data to deduce when bladder opening is appropriate. The valve will be opened by command over a body area network, which Zarlink is working on at its Monmouthshire site.

In total, there are 26 partners - including six SMEs - from ten countries in Healthy Aims, with a total budget, including self-funding, of €26m. "The mix of SMEs and big players in our Sixth Framework programme is unusual, we are a true partnership," says Hodgins. "Usually the programmes are started by big companies and SMEs only get invited in when their technology is needed."

www.healthyaims.org

Healthy Aims products will include:
    Cochlear implants
    Retina implant and glaucoma sensors
    Functional electrical limb stimulators
    Artificial sphincters and sphincter sensors
    Implantable intracranial pressure sensors
    Inertial human motion sensors


Programme members
Austria:
    Universitaet Wien
Belgium:
    Cochlear Technology Centre Europe
    Interuniversitaire Micro-Elektronica Centrum
France:
    The NEXUS Association
    Saft
Germany:
    Campus Micro Technologies
    Hahn-Schickard-Gesellschaft Fuer Angewandte Forschung
    IIP-Technologies
    IMTEK - Institute of Microsystem Technology
    microTEC Gesellschaft fur Mikrotechnologie
    VDI/VDE Technologiezentrum Informationstechnik
Israel:
    Assuta Medical Centers
Poland:
    Instytut Technologii Elektronowej
Spain:
    Universitat Rovira I Virgili
Switzerland:
    Ecole Polytechnique Federale de Lausanne
UK:
    Central Research Labs
    European Technology for Business
    Finetech Medical
    Mediplus
    Queen Mary and Westfield College, University of London
    North Bristol NHS Trust
    Salisbury District Hospital NHS Trust
    TWI
    University of Newcastle upon Tyne
    University of Salford
    Zarlink Semiconductor

 

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